In 1991, hikers discovered the mummified remains of a man who died 5300 years ago in the Alps with an arrow stuck through his shoulder. His genetics show great affinity to modern Sardinia and it is thought if you have ancestors stem from the region between Sardinia and the Alps, there is a chance you could be related to Ötzi. Found in the Ötztal Alps between Italy and Austria, he was given the nickname Ötzi and represents Europe's oldest known natural mummy.

He is believed to have been murdered as the arrowhead in his left shoulder was a fatal wound. He had brown eyes, O-type blood, was lactose intolerant and probably had Lyme disease. Analysis of his colon showed Ötzi's second-to-last meal included ibex meat, cereals and plants. His last meal included red deer meat, grasses and cereals. He had a gap in his smile, lacked wisdom teeth and also had a fairly rare condition where he lacked the smallest ribs on either side.

The future French Revolutionary Jean-Paul Marat left home at the age of 16 to train in medicine and would eventually settle in Newcastle upon Tyne where he gained a reputation as being a highly efficient doctor who also had an interest in political writings. He moved back France 6 years later and his medical skills earned him the patronage of the aristocracy. He used his new found wealth to found a scientific laboratory where he began studies on fire, heat, light and electricity - he was even visited by Benjamin Franklin. Despite his new status and success, he began so spend a lot of time discussing and writing about social injustice.

As Louis XVI struggled to maintain power in the late 1780s by assembling the Estates-General for the first time in 175 years, Marat decided to end his research and medical profession to focus entirely on his passion for politics. He began writing on the topics of social, economic and religious reforms - this manifested itself in numerous vicious attacks on those he proclaimed were enemies of the people. His newspaper called for extreme violence against the upper class and government provoking statements such as five or six hundred heads cut off would have assured your repose, freedom and happiness. After reaching fame, He was elected to the National Convention in 1792 where he actively supported the death of the deposed King in a trial.

French revolutionists condemned King Louis XVI to death on 21. January 1793 by means of the guillotine at the Place de la Revolution in Paris (roughly where the Obelisk decorating the Place de la Concorde stands today). After a short but defiant speech he lost his head as the crowd rushed to the scaffold to dip hankerchiefs into his blood as momentos. An ornate gourd decorated with French Revolution themes was recently uncovered which had contained a blood soaked hankerchief dating to this time. The gourd was allegedly a gift to Napoleon Bonaparte who became First Consul of France in 1799 and Emperor in 1804. An anonymous Italian family was in its posession since possibly the late 1800s and came forward with the relic. It bears an inscription that Maximilien Bourdaloue on 21. January dipped his hankerchief in the blood of the king. Dried blood was scraped out and this is the same DNA we present in this DNA spotlight! The sample contains unsually high and rare markers for the Y-DNA haplogroup G2a.

Louis XVI's direct male line ancestor Henri IV was famous for enacting the Edict of Nantes which guaranteed religious liberties to Protestants ending 30 years of fighting between French Protestants and Catholics - he was assassinated in 1610 by a French Catholic zealot. The remains had been presumed lost in the chaos of the French Revolution after a mob of revolutionaries desecrated the graves of French kings in the royal chapel of Saint-Denis in Paris in 1793. However, the head was passed down over the centuries by secretive private collectors and positively identifed in 2010 with a radiocarbon date between 1450 and 1650. The features were consistent with the king's face including a dark mushroom-like lesion near the right nostrial, a healed facial stab wound and a pierced right earlobe. The hair color and moustache and beard on the mummified head fit the appearance of the king at the time of his death as well as matched his portraits. Furthermore cutting wounds were visible corresponding to the separation of the head from the body in 1793 and digital facial reconstruction of the skull matched the plaster mould of his face made just after his death in 1610. The DNA was then tested and compared to the blood from the gourd.